Small molecule inhibitors of signal transducer and activator of transcription 3 (Stat3) protein

J Med Chem. 2012 Aug 9;55(15):6645-68. doi: 10.1021/jm300207s. Epub 2012 Jun 15.

Authors

Bikash Debnath¹, Shili Xu, Nouri Neamati

Affiliation

¹ Department of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Southern California , 1985 Zonal Avenue, Los Angeles, California 90089, United States.

PMID: 22650325
DOI: 10.1021/jm300207s

No abstract available

Publication types

Review

MeSH terms

Animals
Antineoplastic Agents / chemistry
Antineoplastic Agents / pharmacology
Antineoplastic Agents / therapeutic use
Clinical Trials as Topic
Drug Design
High-Throughput Screening Assays
Humans
Neoplasms / drug therapy
Neoplasms / metabolism
Peptides / chemistry
Peptides / pharmacology
Peptidomimetics / chemistry
Peptidomimetics / pharmacology
Psoriasis / drug therapy
Psoriasis / metabolism
STAT3 Transcription Factor / antagonists & inhibitors*
STAT3 Transcription Factor / chemistry
STAT3 Transcription Factor / physiology
Signal Transduction
Stem Cells / drug effects
Stem Cells / physiology
Structure-Activity Relationship

Substances

Antineoplastic Agents
Peptides
Peptidomimetics
STAT3 Transcription Factor